What does cis mean or stand for, as in cisgender?

Though it does not formally stand for this, it is commonly said to stand for “comfortable in skin.” Basically it means that a natural xx-chromosome girl does not try to pass herself off as a guy or that an xy-chromosome guy doesn’t try to pass himself off as a girl.

By the way, in this case cisgender and specifically cis- is not an abbreviation or acronym but, instead, a Latin prefix that is the opposite of trans-. While trans- means “across,” cis- means “on this side.”

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